Friday, May 26, 2017You are here Products / Antibodies / PROTEIN PROCESSING / MATURATION / DEGRADATION
Print

ABCA1 (Clone AB1.G6)

Mouse Monoclonal Antibody

PRODUCT #: 31-1017

 

DESCRIPTION: Mutations of the ABCA1 gene (ATP-binding cassette transporter 1) are associated with tangier disease (TD). TD is a autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. 

APPLICATIONS/DILUTIONS:    

WB (1:1,000-2,000)

ELISA (3-6 ug/ml)

IP

IHC (1:200)


 

FORM/STORAGE: 50 ug (0.5 mg/ml affinity purified IgG1 in PBS with 50% glycerol, 1.0 mg/ml BSA and 0.01% sodium azide). Store at -20o C. Avoid multiple freeze/thaw cycles.

 

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.