| DESCRIPTION: GFAP is a member of the intermediate filament protein family which includes desmin, peripherin and vimentin. It is a major protein component in multiple sclerosis plaques but is found to be up-regulated in other instances where there has been damage or the occurrence of disease to the nervous system. GFAP is expressed in cells of astrocytic lineage, peripheral ganglia, and non-myelinating Schwann cells. In addition, neural stem cells also express GFAP. |
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| SPECIES CROSS-REACTIVITY: |
Mammalian, avian |
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| APPLICATIONS / DILUTIONS: |
ICC/IF (1/200 – 1/1,000)
WB (1/10,000) |
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| SOURCE: |
Chickens were immunized with purified bovine spinal cord GFAP. |
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| FORM / STORAGE: |
0.1 ml with 50% glycerol and 0.01% sodium azide. Store at -20º C. Avoid multiple freeze/thaw cycles. Immunoglobulin isotype is IgY. |
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THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.
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