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DESCRIPTION: GAP-43 is axonal membrane phosphoprotein considered to be a plasticity or growth protein because it is highly expressed in neuronal growth cones during development an axonal elongation during regeneration. It is involved in long-term potentiation and plays a role in synapse formation. Expression of GAP-43 is limited to the nervous system.
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SPECIES CROSS-REACTIVITY:
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Mam, Ck
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| APPLICATIONS/DILUTIONS: |
ICC/IF (2.0 - 4.0 ug/ml)
WB (0.5 – 2.0 ug/ml)
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| SOURCE: |
Rabbits were immunized with a synthetic peptide corresponding to amino acid residues 216-226 of rat and mouse GAP-43. n-(C)KE DPE ADQ EHA-c
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| FORM/STORAGE: |
0.2 ml (1.0 mg/ml) with 50% glycerol and 0.01% sodium azide. Store at -20º C. Avoid multiple freeze/thaw cycles.
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Mouse gut neurons in the gut of developing mouse. Immunoperoxidase stain with the anti-GAP-43 (1:500). Image kindly provided by Dr. David F. Muir, University of Florida
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.
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