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Growth-Associated Protein-43 (GAP-43)

Rabbit Polyclonal Antibody

PRODUCT #: 24-5678

 

DESCRIPTION: GAP-43 is axonal membrane phosphoprotein considered to be a plasticity or growth protein because it is highly expressed in neuronal growth cones during development an axonal elongation during regeneration. It is involved in long-term potentiation and plays a role in synapse formation. Expression of GAP-43 is limited to the nervous system.
 

SPECIES CROSS-REACTIVITY:

Mam, Ck
 

APPLICATIONS/DILUTIONS:

ICC/IF (2.0 - 4.0 ug/ml)
WB (0.5 – 2.0 ug/ml)
 

SOURCE:

Rabbits were immunized with a synthetic peptide corresponding to amino acid residues 216-226 of rat and mouse GAP-43. n-(C)KE DPE ADQ EHA-c
 

FORM/STORAGE:

0.2 ml (1.0 mg/ml) with 50% glycerol and 0.01% sodium azide. Store at -20º C. Avoid multiple freeze/thaw cycles.
 

 

Mouse gut neurons in the gut of developing mouse. Immunoperoxidase stain with the anti-GAP-43 (1:500). Image kindly provided by Dr. David F. Muir, University of Florida

 

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.