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Lipoprotein Lipase (Clone LPL.A4)

Mouse Monoclonal Antibody

PRODUCT #: 31-1018

 

DESCRIPTION: Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by the macrophages in the vessel wall exerts proatherogenic ecffects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within the macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimiulation of tumor necrosis factor alpha (TNF) secretion and induction of vascular smooth musclr cell proliferation. 

SPECIES CROSS-REACTIVITY: Human, bovine
APPLICATIONS/DILUTIONS:    

WB (1:100-250)

ELISA (1-2000-5000)

 

SOURCE: Human LPL whole protein.
FORM/STORAGE: 50 ug (0.5 mg/ml affinity purified IgG1 in PBS with 50% glycerol, 1.0 mg/ml BSA and 0.01% sodium azide). Store at -20o C. Avoid multiple freeze/thaw cycles.

 

THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.