DESCRIPTION: Neurofilaments are members of the intermediate filament protein family and are neuron-specific. There are three major proteins, NF-H, NF-L and NF-M. Accumulation of neurofilaments is observed during the progression of numerous neurological diseases. This antibody recognizes phosphorylated NF-H sequence n-KSP-c (lysine-serine-proline). Some cross-reactivity to the phosphorylated n-KSP-c of subunit unit NF-M may be observed in some species.

Mam, Ck

ICC/IF (1/100 – 1/500)
WB (1/1,000 – 1/2,500)

Mice were immunized with purified pig spinal cord NF-H.

0.1 ml with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. Immunoglobulin isotype is IgG1.