DESCRIPTION: Neurofilaments are members of the intermediate filament protein family and are neuron-specific. There are three major proteins, NF-H, NF-L and NF-M. Accumulation of neurofilaments is observed during the progression of numerous neurological diseases. This antibody recognizes phosphorylated NF-H sequence n-KSP-c (lysine-serine-proline). Some cross-reactivity to the phosphorylated n-KSP-c of subunit unit NF-M may be observed in some species.
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SPECIES CROSS-REACTIVITY: |
Mam, Ck
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APPLICATIONS/DILUTIONS: |
ICC/IF (1/100 – 1/500)
WB (1/1,000 – 1/2,500)
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SOURCE: |
Mice were immunized with purified pig spinal cord NF-H.
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FORM/STORAGE: |
0.1 ml with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. Immunoglobulin isotype is IgG1.
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THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES.
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