DESCRIPTION: Ubiquitin is a highly conserved 76 amino acid protein which is covalently coupled to proteins targeted for degradation by the proteasome, a normal physiologic process. In some cases, including those associated with pathological conditions, ubiquitin accumulation has been observed. This phenomenon has been seen in Alzheimer’s and Parkinson’s disease progression.
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SPECIES CROSS-REACTIVITY: |
Broad
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APPLICATIONS/DILUTIONS: |
IHC/IF (1/250 – 1/5,000)
WB (1/500 – 1/2,500)
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SOURCE: |
Mice were immunized with purified ubiquitin conjugated to keyhole limpet hemocyanin.
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FORM/STORAGE: |
0.1 ml with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. Immunoglobulin isotype is IgG1.
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THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN HUMANS OR DIAGNOSTIC PROCEDURES. |