DESCRIPTION: Ubiquitin is a highly conserved 76 amino acid protein which is covalently coupled to proteins targeted for degradation by the proteasome, a normal physiologic process. In some cases, including those associated with pathological conditions, ubiquitin accumulation has been observed. This phenomenon has been seen in Alzheimer’s and Parkinson’s disease progression.

Broad

IHC/IF (1/250 – 1/5,000)

WB (1/500 – 1/2,500)

Mice were immunized with purified ubiquitin conjugated to keyhole limpet hemocyanin.

0.1 ml with 50% glycerol, 0.01% sodium azide and 1.0 mg/ml BSA. Store at -20º C. Avoid multiple freeze/thaw cycles. Immunoglobulin isotype is IgG1.